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Avanafil is a PDE5 inhibitor for erectile dysfunction.
Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are sildenafil, tadalafil and vardenafil.
The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.


  1. Avanafil is a kind of phosphodiesterase 5 (PDE5) inhibitor, Used to treat male erectile dysfunction (ED).
  2. Avanafil can promote the hard penis enlargement.

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